The annual assembly of the Italian Society of Interventional Cardiology (GISE) held in Milan this year from October 3 to 6, provided a comprehensive overview of cutting-edge interventions in cardiovascular care. This significant gathering brought together experts, medical practitioners, and enthusiasts, focusing on acute coronary syndromes (ACS), innovative procedural techniques, and recent breakthroughs in cardiovascular care. The event saw a number of dedicated sessions exploring topics such as innovative strategies for complete revascularization, bridging therapies, and addressing challenges associated with percutaneous coronary intervention (PCI), particularly in dealing with calcified lesions and bifurcations. Active participation from nurses and technicians underscored the importance of the ABCs (knowledge, skills, and attitude) in Emodinamica. Discussions spanned from managing severe femoropopliteal calcifications to evolving techniques in coronary pathophysiology assessment, offering valuable insights into the management of structural heart disease beyond device-focused considerations. The conference extended its reach beyond coronary interventions, featuring skill and technology sessions covering diverse themes. These encompassed the management of complex degenerative mitral regurgitation, exploration of radial access for carotid stenting, and resolution of severe femoropopliteal calcifications. Additionally, the agenda explored the intricacies of revascularizing chronic limb-threatening ischemia. In the clinical spotlight, discussions ranged from antiplatelet therapy in ACS to the role of newer lipid-lowering therapies. Critical topics such as the management of left main coronary disease, intravascular imaging in complex PCI, and contemporary approaches to the treatment of acute pulmonary embolism were explored. A notable development happened during the congress was the election of Francesco Saia as the new president of the Italian Society of Interventional Cardiology. New President Saia graduate in medicine from the University of Bologna in 1995, specialized in Cardiology in 2000, and holding two research doctorates, President Saia currently serves as an Interventional Cardiologist at IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola in Bologna, and he also cover the role of university researcher at University of Bologna. Looking forward, Saia’s strategic vision for the future of Interventional Cardiology centers around four key pillars. These include, increasing therapeutic options for structural interventional procedures, leveraging opportunities presented by technology and digital development, utilizing existing networks for acute myocardial infarction to enhance the treatment of severe cases of pulmonary embolism, and decisively addressing gender medicine, especially in the realm of Interventional Cardiology.